Neoadjuvant chemotherapy versus chemoradiotherapy for esophageal cancer: a tradeoff between dysphagia and pathologic response
نویسندگان
چکیده
منابع مشابه
Effect of neoadjuvant chemoradiotherapy on pathologic stage and survival in patients with locally advanced esophageal cancer.
4032 Background: The strongest predictor of survival in patients with locally advanced esophageal cancer treated with primary surgical resection is stage. This study aimed to determine if surgical stage after pre-operative chemoradiotherapy predicted a similar survival pattern. METHODS Patients (n=42) received cisplatin, 5-FU and radiotherapy (RT) followed by esophagectomy. Pre- and post-trea...
متن کاملPathologic and Oncologic Outcomes in Locally Advanced Gastric Cancer with Neoadjuvant Chemotherapy or Chemoradiotherapy
PURPOSE Although neoadjuvant therapy has been accepted as a treatment option in locally-advanced gastric cancer, its prognostic value has been difficult to evaluate. MATERIALS AND METHODS Seventy-four gastric cancer patients who underwent gastrectomy after neoadjuvant treatment were divided into two groups according to the pathologic response: favorable (ypT0) and others (ypT1-4). The clinico...
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PURPOSE Pathologic complete response (pCR) to neoadjuvant chemotherapy reflects the cytotoxic efficacy of a drug, but patient survival is influenced by many other factors. The purpose of this study was to assess the relationship between increased pCR rate and trial-level survival benefit in triple-negative breast cancer (TNBC). EXPERIMENTAL DESIGN We used bootstrap resampling from a neoadjuva...
متن کاملPositron emission tomography for predicting pathologic response after neoadjuvant chemoradiotherapy for locally advanced rectal cancer.
PURPOSE To investigate whether before and after chemoradiotherapy (CRT) positron emission tomography (PET) predict for pathologic response after preoperative CRT in patients with locally advanced rectal adenocarcinoma. METHODS Thirty-five patients who underwent pre-CRT and post-CRT PET scans before surgery were included. All patients were staged with endoscopic ultrasound or high resolution C...
متن کاملNeoadjuvant chemotherapy and pathologic response: a retrospective cohort
OBJECTIVE To evaluate the complete pathologic response attained by patients diagnosed with locally advanced breast cancer submitted to neoadjuvant chemotherapy based on the doxorubicin/cyclophosphamide regimen followed by paclitaxel. METHODS A retrospective cohort of patients with locally advanced breast cancer, admitted to the Hospital de Câncer de Barretos between 2006 and 2008 submitted to...
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ژورنال
عنوان ژورنال: Video-Assisted Thoracic Surgery
سال: 2018
ISSN: 2519-0792
DOI: 10.21037/vats.2018.12.02